 92% Success Rate
 Average Monthly Weight Loss: 12-16 LBS
 All Natural

What is Semaglutide/Tirzepatide?

Semaglutide/Tirzepatide an incretin mimetic; specifically, semaglutide is a GLP-1 receptor agonist with 94% sequence homology to human GLP-1. Semaglutide binds and initiates the GLP-1 receptor. GLP-1 is an important, gut-derived, glucose homeostasis regulator that is released after the oral ingestion of carbohydrates or fats. In patients with Type 2 diabetes, GLP-1 concentrations are decreased in response to an oral glucose load. GLP-1 enhances insulin secretion; it increases glucose-dependent insulin synthesis and in vivo secretion of insulin from pancreatic beta cells in the presence of elevated glucose. In addition to increases in insulin secretion and synthesis, GLP-1 suppresses Glc secretion, slows gastric emptying, reduces food intake, and promotes beta-cell proliferation. The principal mechanism of protraction resulting in the long half-life of semaglutide is albumin binding, which results in decreased renal clearance and protection from metabolic degradation; semaglutide is stabilized against degradation by the DPP-4 enzyme. Semaglutide reduces blood glucose through a mechanism where it stimulates insulin secretion and lowers Glc secretion, both in a glucose-dependent manner. Therefore, when blood glucose is high, insulin secretion is stimulated and Glc secretion is inhibited. The mechanism of blood glucose lowering also involves a minor delay in gastric emptying in the early postprandial phase.

Purpose

Semaglutide/Tirzepatide Injection works by simulating hormones that affect areas of the brain involved in regulating appetite and food intake. This can help you eat less and lead to weight loss.

Benefits

– Weight Loss

– May improve Blood Pressure

– May improve cholesterol

– Improves Blood Sugar

**Must have a BMI OF 27 OR GREATER**

Reference:

https://pubmed.ncbi.nlm.nih.gov/33567185/

https://pubmed.ncbi.nlm.nih.gov/33755728/